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What causes the Gmail DSN 421-4.3.0 temporary system problem and how to resolve it?

Summary

The Gmail DSN 421-4.3.0 temporary system problem arises from a multitude of causes, broadly categorized as issues on Google's side, server-side problems, sender-side configurations, and network-related issues. Server-side problems encompass temporary server unavailability, overload, or maintenance. Sender-side issues include rate limiting, poor IP reputation, exceeding connection limits, incorrect SPF records, insufficient server resources, greylisting, shared IP limitations, throttling, and temporary TLS issues. Resolution strategies vary but often involve retrying the email, addressing SPF configuration, monitoring IP reputation, managing sending volume, ensuring sufficient server resources, and investigating potential greylisting or TLS issues.

Key findings

  • Google-Side Issues: Temporary problems internal to Google's infrastructure can trigger the 421 error, as highlighted by Google's incident reports.
  • Server Unavailability: Receiving servers may temporarily reject connections due to being too busy or undergoing maintenance.
  • Rate Limiting & Throttling: Exceeding sending rate limits or being throttled by Gmail can cause temporary rejections.
  • Reputation Impact: A poor IP reputation, often stemming from spam-like behavior, can result in temporary rejections from receiving servers.
  • Configuration Issues: Incorrect SPF records, exceeding connection limits, and temporary TLS issues contribute to 421 errors.
  • Resource Limitations: Insufficient server resources or memory can result in temporary connection rejections.
  • Greylisting: Greylisting, a spam-fighting technique, initially rejects emails from unknown senders.

Key considerations

  • Retry Sending: Always retry sending the email after a short delay, as many causes are transient.
  • Monitor Reputation: Regularly monitor IP and domain reputation to identify and address potential issues.
  • Check SPF Records: Ensure SPF records are correctly configured and up-to-date.
  • Adjust Sending Volume: Implement gradual email sending strategies to avoid exceeding rate limits or triggering throttling.
  • Investigate Greylisting: If greylisting is suspected, ensure proper retry mechanisms are in place.
  • TLS Configuration: Check the TLS configuration to ensure encryption occurs seamlessly and to prevent errors.
  • Server Resources: Make sure your server or esp provider have enough resources to handle the sending volume.

What email marketers say

14 marketer opinions

The Gmail DSN 421-4.3.0 temporary system problem is a transient issue that can arise from various causes, including temporary server issues, rate limiting, reputation problems, exceeding connection limits, incorrect SPF records, insufficient server resources, greylisting, shared IP limitations, and throttling by Google/Gmail. Resolution often involves retrying the email send later, ensuring proper authentication, monitoring sender reputation, correctly configuring SPF records, increasing server resources, and gradually sending emails to avoid throttling.

Key opinions

  • Temporary Server Issues: The 421 error often indicates temporary problems on the receiving server, such as being busy or unavailable.
  • Rate Limiting: Sending too many emails in a short period can trigger rate limiting, causing the server to temporarily refuse connections.
  • Reputation Issues: A low sender reputation or recent blacklisting of the sending IP address can lead to temporary rejections.
  • Connection Limits: Exceeding connection limits or attempting to relay without proper authentication can cause a 421 error.
  • Incorrect SPF Records: Improperly configured SPF records can result in temporary rejections.
  • Insufficient Server Resources: Overloaded servers or those running out of memory may temporarily reject connections.
  • Greylisting: Greylisting mechanisms intentionally defer delivery attempts from unknown senders.
  • Shared IP Limitations: Senders on shared IPs can experience issues if other users on the same IP engage in poor sending practices.
  • Throttling: Google/Gmail's throttling mechanisms limit the number of emails sent per period, which can trigger 421 errors.

Key considerations

  • Retry Sending: For temporary server issues, retry sending the email after a short delay.
  • Monitor Reputation: Regularly monitor sender reputation and address any issues promptly.
  • Configure SPF: Ensure SPF records are correctly configured to authorize sending servers.
  • Adjust Sending Rate: Reduce the sending rate to avoid triggering rate limiting.
  • Increase Resources: If server resources are insufficient, consider increasing them.
  • Authentication: Check sending server configuration and authentication.
  • Gradual Sending: Implement gradual email sending strategies to avoid throttling.

Marketer view

Email marketer from Email Geeks confirms that the issue could be due to continued sending to over-quota/out-of-storage mailboxes.

24 Dec 2023 - Email Geeks

Marketer view

Email marketer from StackExchange suggests that greylisting mechanisms often cause 421 errors as a deliberate measure to filter spam. These mechanisms defer delivery attempts from unknown senders, expecting legitimate mail servers to retry sending.

12 May 2025 - StackExchange

What the experts say

3 expert opinions

The Gmail DSN 421-4.3.0 temporary system problem is caused by a variety of factors, including greylisting, temporary server issues (overload, maintenance, network problems), and temporary TLS issues. Resolution typically involves retrying the message delivery after some time and addressing TLS configuration issues if present.

Key opinions

  • Greylisting: Greylisting, a spam-fighting technique, temporarily rejects emails from unknown senders, leading to 421 errors.
  • Temporary Server Issues: Server overload, maintenance, or network problems can cause temporary 421 errors.
  • Temporary TLS Issues: Temporary TLS configuration problems can result in 421 errors during email transmission.

Key considerations

  • Retry Sending: If the 421 error is due to a temporary server issue or greylisting, retry sending the message after some time.
  • Check TLS Configuration: Investigate and address any TLS configuration issues that may be causing temporary failures.
  • Monitor Server Load: Ensure server has sufficient resources to be able to handle load.

Expert view

Expert from Word to the Wise highlights that temporary TLS issues can result in 421 errors. Configuration issues can cause the encryption to fail temporarily.

7 Jul 2023 - Word to the Wise

Expert view

Expert from Spam Resource clarifies that the 421 status code indicates a temporary issue, such as server overload, maintenance, or network problems. Retrying the message delivery after some time is recommended.

5 Sep 2024 - Spam Resource

What the documentation says

5 technical articles

The Gmail DSN 421-4.3.0 temporary system problem is a transient error indicating temporary issues on Google's side, with the remote host, or within the transport layer (DNS, network timeouts). Documentation advises retrying the connection later as the primary course of action. The error generally resolves itself, and further action is not typically required.

Key findings

  • Transient Issue: The 421 error indicates a transient or temporary problem.
  • Google's Side: The error can originate from issues on Google's side.
  • Remote Host Problems: Temporary problems with the remote host or connection are common causes.
  • Transport Layer Issues: DNS resolution failures and network timeouts can also lead to this error.
  • Service Unavailable: Indicates that the service is not available and the connection will be closed.

Key considerations

  • Retry Connection: Retry the connection after a few minutes, as the issue is often temporary.
  • No Action Required: Further action is generally not required from the user, as the error typically resolves itself.
  • Monitor DNS: If the problem persists, monitor DNS resolution and network connectivity.

Technical article

Documentation from Microsoft Learn indicates a 421 SMTP response code generally indicates that the service is not available and the connection will be closed. The application should retry.

22 Feb 2023 - Microsoft Learn

Technical article

Documentation from Exim Wiki explains that the 421 error is often seen when there are temporary problems with the remote host or the connection to it. This could be due to network congestion, server overload, or temporary unavailability. Retrying the connection later is advised.

23 Mar 2022 - Exim Wiki

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