Email marketers should address permanent bounce errors, such as full or inactive mailboxes, promptly to maintain sender reputation and improve deliverability. The primary recommendation is to immediately remove hard-bouncing addresses from mailing lists, often automating this process. Gmail distinguishes between temporary and permanent full mailbox bounces using different error codes (4.x.x vs. 5.x.x). Before complete removal, some suggest attempting re-engagement based on user actions (login, purchase, click), but this strategy depends on client preferences. Crucial proactive measures include implementing double opt-in, regularly cleaning email lists, authenticating emails (SPF, DKIM, DMARC), monitoring sender scores, and focusing on engagement metrics. Providing website feedback about bounced emails can also enhance user awareness.