Exceeding email size limits and causing clipping can negatively impact email deliverability and sender reputation through multiple pathways. While some experts suggest that clipping's primary impact is on open tracking or display, the consensus is that large emails, particularly those with poor coding or excessive images, can increase spam scores, trigger filters, and reduce engagement. Ensuring emails stay within provider limits, simplifying designs, optimizing images, and avoiding large attachments are crucial strategies to mitigate these risks and maintain a healthy sender reputation.