Emailing users inactive for 4+ years is generally considered detrimental to email deliverability and sender reputation. Experts and marketers advise against this practice due to risks such as increased spam complaints, hitting spam traps, and damaging sender reputation, potentially leading to deliverability issues. The consensus is that inactive users are less likely to remember subscribing, more likely to mark emails as spam, and may have abandoned their email addresses, which could now be spam traps. Instead of directly emailing these users, it is recommended to implement a sunset policy, re-engage them through targeted campaigns, reconfirm consent, and remove those who don't respond. Regularly cleaning email lists by removing inactive subscribers is also crucial for maintaining a healthy sender reputation, improving engagement rates, increasing conversions, and protecting against potential security risks.